everslim Quattro vs Direct Meds DirectMax: ED Treatment Comparison
Direct Meds' DirectMax (marketed as a "3-in-1 Rapid Dissolve ED Medication") and everslim's Quattro are both compounded combination treatments for ED taken under the tongue, and both include apomorphine. Here are the published facts side by side.
Head-to-head: Quattro vs DirectMax
Prices are per brand unit (vial, troche, lozenge or chew), not per mg, and are compared on the same plan length. “Reported” means the brand did not publish the figure and we cite who did. Competitor details checked October 28, 2026. Both products are compounded medications, which are not FDA-approved; the FDA does not review them for safety, effectiveness or quality.
What they have in common
Both contain apomorphine, sildenafil and tadalafil, both dissolve under the tongue, and both are prescribed only after an online assessment reviewed by a licensed provider. Both are compounded medications, which are not FDA-approved.
Where they differ
The differences are in the fourth active, the format and how much of the pricing is published.
- Four actives vs threeQuattro adds vardenafil to the three actives DirectMax contains.
- Liquid vial vs tabletQuattro is a liquid in a single-dose vial. DirectMax is a rapid-dissolve tablet.
- Published pricingQuattro lists monthly and 3-month prices on its page. Direct Meds' own site did not show DirectMax prices when we checked; the $8.78 figure comes from a sponsored article.
Where Quattro differs
- Four prescription actives. Apomorphine, sildenafil, tadalafil and vardenafil.
- $7.00 a dose monthly, $4.67 on 3 months. DirectMax: $8.78 a dose reported for the Low tier, plan length not stated.
- Named pharmacies. Quattro is compounded by EPIQ Scripts, Foothills Pharmacy and Emerald Compounding.
In short
Both are under-the-tongue combinations with apomorphine. Quattro has one more active and a price you can see before you start. Quattro's smallest plan is 20 doses, so its monthly cart ($140) is larger than most. The per-dose price is where it comes out lower.
Start your Quattro consultation
How to get Quattro
- 01Online assessmentA few minutes of questions about your health and goals. No video call in most states.
- 02Provider reviewA licensed US provider reviews your answers and decides whether Quattro is right for you.
- 03Discreet deliveryIf prescribed, a US pharmacy ships it to your door in plain packaging.
See if Quattro is right for you
Sources and notes
Direct Meds DirectMax details are from directmeds.com, Direct Meds' August 2026 release and sponsored DirectMax pricing article, checked October 28, 2026. Brands change formulas and prices, so check theirs before you decide. Direct Meds and DirectMax are trademarks of their owners, used here only to identify their product. everslim is not affiliated with Direct Meds.
Quattro and Direct Meds DirectMax are compounded medications. Compounded medications are not FDA-approved, and the FDA does not verify their safety, effectiveness or manufacturing quality. A prescription is only written if a licensed provider decides it is appropriate, and results vary. everslim is not a pharmacy: Quattro is compounded and dispensed by licensed US pharmacies (EPIQ Scripts, Foothills Pharmacy, Emerald Compounding).
*$4.67 a dose is the 20-dose pack on the 3-month plan: 60 doses billed $280 upfront ($93.33 a month). The 1-month plan is $140 for 20 doses. You are only charged if a provider prescribes.
Prescription ED medications are not for everyone. Do not use them if you take nitrates for chest pain or guanylate cyclase stimulators such as riociguat, because the combination can cause a dangerous drop in blood pressure. Tell your provider about every medication and supplement you take, and about any medical conditions, especially heart problems, low or high blood pressure, a recent heart attack or stroke, kidney or liver disease, or eye conditions.
Seek emergency care for an erection lasting more than 4 hours, sudden loss of vision or hearing, chest pain, fainting or severe dizziness. Common side effects can include headache, flushing, indigestion, nasal congestion, back pain, nausea and dizziness.
Timing and results vary from person to person. Your provider decides whether treatment is appropriate and at what dose. This page is general information and not medical advice.
everslim does not make compounded medications. Prescriptions are filled by licensed US compounding pharmacies, each with its own packaging, so what arrives may look different from what is shown here. Certain images on this page are AI-generated or enhanced, and people shown may be models. Reviews are from customers and describe individual experiences.
