everslim Quattro vs Ro Sparks: Actives, Format and Price per Dose

Ro Sparks and everslim's Quattro are both compounded combination treatments for ED taken under the tongue. Sparks combines two PDE5 inhibitors. Quattro combines three, plus apomorphine. Here are the published facts side by side.
Head-to-head: Quattro vs Sparks
Prices are per brand unit (vial, troche, lozenge or chew), not per mg, and are compared on the same plan length. “Reported” means the brand did not publish the figure and we cite who did. Competitor details checked October 28, 2026. Both products are compounded medications, which are not FDA-approved; the FDA does not review them for safety, effectiveness or quality.
What they have in common
Both contain sildenafil and tadalafil, both are taken under the tongue, and both are prescribed only after an online assessment reviewed by a licensed provider. Both are compounded medications, which are not FDA-approved.
Where they differ
The differences are in the number of actives, the format and the price per dose.
- Four actives vs twoQuattro adds apomorphine, a dopamine agonist that acts in the brain, and vardenafil, a third PDE5 inhibitor. Sparks contains sildenafil 55 mg and tadalafil 22 mg.
- Liquid vial vs lozengeQuattro is a liquid in a single-dose vial. Sparks is a lozenge, which Ro markets as drops.
- Price per doseOn monthly plans, Quattro is $7.00 a dose and Sparks $12.00. On 3-month plans, Quattro is $4.67 and Sparks from $10.75.
Where Quattro differs
- Four prescription actives. Apomorphine, sildenafil, tadalafil and vardenafil.
- $7.00 vs $12.00 a dose on monthly plans. Quattro: $140 for 20 doses. Sparks: $48 for 4 doses up to $168 for 14.
- $4.67 vs $10.75 a dose on 3-month plans. Quattro: $280 for 60 doses. Sparks: $129 for 12.
- Named pharmacies. Quattro is compounded by EPIQ Scripts, Foothills Pharmacy and Emerald Compounding.
In short
Sparks is a two-active lozenge; Quattro is a four-active liquid that costs less per dose on both monthly and 3-month plans. Ro's smallest plan is 4 doses for $48. Quattro's smallest plan is 20 doses, so its monthly cart ($140) is larger than most. The per-dose price is where it comes out lower.
Start your Quattro consultation
How to get Quattro
- 01Online assessmentA few minutes of questions about your health and goals. No video call in most states.
- 02Provider reviewA licensed US provider reviews your answers and decides whether Quattro is right for you.
- 03Discreet deliveryIf prescribed, a US pharmacy ships it to your door in plain packaging.
See if Quattro is right for you
Sources and notes
Ro Sparks details are from Ro's Sparks safety information and Ro's ED pricing page, checked October 28, 2026. Brands change formulas and prices, so check theirs before you decide. Ro and Sparks are trademarks of their owners, used here only to identify their product. everslim is not affiliated with Ro.
Quattro and Ro Sparks are compounded medications. Compounded medications are not FDA-approved, and the FDA does not verify their safety, effectiveness or manufacturing quality. A prescription is only written if a licensed provider decides it is appropriate, and results vary. everslim is not a pharmacy: Quattro is compounded and dispensed by licensed US pharmacies (EPIQ Scripts, Foothills Pharmacy, Emerald Compounding).
*$4.67 a dose is the 20-dose pack on the 3-month plan: 60 doses billed $280 upfront ($93.33 a month). The 1-month plan is $140 for 20 doses. You are only charged if a provider prescribes.
Prescription ED medications are not for everyone. Do not use them if you take nitrates for chest pain or guanylate cyclase stimulators such as riociguat, because the combination can cause a dangerous drop in blood pressure. Tell your provider about every medication and supplement you take, and about any medical conditions, especially heart problems, low or high blood pressure, a recent heart attack or stroke, kidney or liver disease, or eye conditions.
Seek emergency care for an erection lasting more than 4 hours, sudden loss of vision or hearing, chest pain, fainting or severe dizziness. Common side effects can include headache, flushing, indigestion, nasal congestion, back pain, nausea and dizziness.
Timing and results vary from person to person. Your provider decides whether treatment is appropriate and at what dose. This page is general information and not medical advice.
everslim does not make compounded medications. Prescriptions are filled by licensed US compounding pharmacies, each with its own packaging, so what arrives may look different from what is shown here. Certain images on this page are AI-generated or enhanced, and people shown may be models. Reviews are from customers and describe individual experiences.
